gwern comments on Cascio in The Atlantic, more on cognitive enhancement as existential risk mitigation - Less Wrong
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Hm, where's the Conrad ref? I see a God Emperor of Dune ref (Dune seems pretty popular here, I've noticed), but not that.
It's the whited sepulchre thing; it's one of the central themes of Heart of Darkness. (Google tells me the original quote is from Matthew 23:27).