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Annoyance comments on Is it rational to take psilocybin? - Less Wrong
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Does psilocybin get classified as a "random modification of your mind" any more than a trip to India does? Surely both could be dangerous?
Self-reported values are all we we have, really - if you want better evidence, you might have to wait for quite a while.
A trip to India isn't optimized for messing with your mind, it isn't expected to impose significantly more change on your cognition than commuting to work and watching a new movie. Better than self-reported values, we have status quo as the guiding principle: if you don't know how to hack a system, leave it alone until you do. Don't rely on the temperature of processor to debug the new superb modification you invented for your program.
If I visited India, I would expect it to result in significantly greater changes to my cognition than commuting to work or watching a new movie.
People take coffee to stimulate themselves, and alcohol for social lubrication. Is that "hacking" too? We know a lot about the effects of many drugs. For many people, the knowledge that we already have is enough for them to decide.