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Annoyance comments on Is it rational to take psilocybin? - Less Wrong
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Here are better primary sources:
The Johns Hopkins Study: http://www.hopkinsmedicine.org/Press_releases/2006/GriffithsPsilocybin.pdf Commentary: http://www.hopkinsmedicine.org/Press_releases/2006/GriffithsCommentaries.pdf
"How can I be more rational from a drug?"
In the short term, ingesting sugar will boost your capacity for handling complexity.
"I doubt a psychedelic experience can help me optimize my current utility function better than my sober self. How can I be more rational from a drug?"
WTF, dude? Not everything in life is about improving your rationality. Do you expect to become more rational after eating a hot dog? How about a peach?
The entire point of being rational is to maximize your expected life value.
If taking psilocybin increases your expected life value by construction you would be irrational not to take it... unless you place a high value on passing up "at least a moderate increase in well-being or life satisfaction".
"The entire point of being rational is to maximize your expected life value."
That may be your purpose of being rational, but I don't see how that follows necessarily. The purpose of being rational is to consciously know what you're arguing and why. There are many potential reasons why that could be a useful strategy.