Annoyance comments on Book Review: Complications - Less Wrong
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Yes, but they're also the sum of prejudices, irrational convictions, short-circuited reasoning processes, and other biases.
Gawande discusses the decision to try to remove only the affected tissue rather than go for amputation - a decision which seems to work out. Then he asks how he and the other doctors knew they could spare the leg.
That's a fundamental failure, changing a guess to knowledge in highsight.