These three are all basically honest, but their effects are unpredictable. 6 and especially 4 may actually make the patient significantly worse off, since the first is evasive and abrasive, and the second is meaningless and prone to misinterpretation ("chloridated alkali metal!? I had no idea it was that serious!"). 5 does no harm, but likely does little good and may be seen as evasive. Given that placebos can actually still work when people know they are recieving them, 1 may be better than all these options, as may 1+3, which seems essentially honest.