timtyler comments on Our society lacks good self-preservation mechanisms - Less Wrong
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Toba supereruption and genetic bottleneck probably strongest example of near-miss.
The genetic bottleneck around the time of the eruption was not as "near" as all that - in part since there were Neanderthals around at that time as an additional backup mechanism, complementing the surviving humans. Plus, of course, Homo floresiensis! ;-)
http://en.wikipedia.org/wiki/Toba_catastrophe_theory estimates we got down to the last 5,000-10,000 backup copies of the human genome.
Figures from before the eruption appear to have not been dramatically higher:
There just weren't that many homos around at the time.