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taw comments on The Obesity Myth - Less Wrong
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Fat is trivial to manipulate. I lost 27kg (BMI 30 to 22) without any effort with ECA (with non-junk diet and a light amounts of exercise, nothing unusual), it's stable for many years now. Just ask any bodybuilders for advice - they know how to do it, or read pubmed about ECA. The difficult part is not believing the popular culture's completely ineffective methods, once you do that losing your fat is trivial matter.
While that may work for you, things like ECA have significant side effects for many people, especially those who have already developed weight-related illnesses, and there are some people for whom they don't work. Given the effectiveness of the pharmaceutical industry in marketing medications, even non-prescription ones, the strong desires of millions of people to lose weight, and the length of time ECA products have been available, it seems unlikely that they are really as effective as you claim.
That's a ridiculously strong version of efficient (medical) market hypothesis. As I said, ECA is semi-legal in States, and its marketing for weight loss is not allowed by FDA. Also, as a non-patented drug, medical industry has absolutely zero incentive to advertise it.
As far as anecdotes go, so far one person on lesswrong tried ECA, and got back to me saying it didn't work. Turned out it was very low dosage ECA and on doubling it there were instant effects.
If you have weight problems, just go ahead, try it, and then tell me it didn't work. That will be unlikely.