In particular, Diamond (I believe, though it's been a while since I read GG&S) argues that wheels have far less obvious utility for vehicles if you don't have pack animals, and therefore don't think in terms of animal-powered transport apart from carrying.
A wheelbarrow is a very useful thing. You don't need an animal to pull a cart in order for it to be worthwhile. I actually think it's quite mysterious that those civilisations invented the wheel, and then didn't bother to use it.
We have a sample of one modern human civilization, but there are some hints on how likely it was to happen.
Major types of hints are:
Data for:
Data against:
To me it looks like life, animals with nervous systems, Upper Paleolithic-style Homo, language, and behavioral modernity were all extremely unlikely events (notice how far ago they are - vaguely ~3.5bln, ~600mln, ~3mln, ~200k or ~600k, ~50k years ago) - except perhaps language and behavioral modernity might have been linked with each other, if language was relatively late (Homo sapiens only) and behavioral modernity more gradual (and its apparent suddenness is an artifact). Once we have behavioral modernity, modern civilization seems almost inevitable. Your interpretation might vary of course, but at least now you have a lot of data to argue for your position, in convenient format.