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wedrifid comments on When Willpower Attacks - Less Wrong
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There has been plenty of research, complete with assigning numbers to the expected IQ drop. From what I recall, acute sleep deprivation has been found to lower measured IQ for up to a week.
(This is without the sleep effects that are particular to modafinil, as opposed to other stimulants such as caffeine or amphetamine.)
If people will forgive me not digging up the details likepage number & citation & metrics, I recall that the big USAF study on modafinil and sleep deprivation found that mental performance on modafinil did begin declining during and past the first night, it just declined less than the alternatives.