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Eliezer_Yudkowsky comments on Open Thread: October 2009 - Less Wrong
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1) I can't work and starve at the same time.
2) State of evidence in favor of CR wasn't very good last time I checked. I recall something along the lines of, "Cutting calories by 40% extends the lifespan of (some short-lived creature) by a week, and it's looking like it may extend human lifespan by a week as well."
Update: Gregory Benford (who recently founded a life extension company) says that CR slows down life processes in both flies and humans. You live longer but you're less active. Sounds plausible.