LauraABJ comments on Dying Outside - Less Wrong

179 Post author: HalFinney 05 October 2009 02:45AM

You are viewing a comment permalink. View the original post to see all comments and the full post content.

Comments (86)

You are viewing a single comment's thread. Show more comments above.

Comment author: LauraABJ 07 October 2009 11:34:03AM 5 points [-]

Well, the facial muscles are innervated by cranial nerves, which do not run through the spinal column (the L in ALS stands for 'lateral' referring to the disintigration of the lateral portion of spinal cord), and the eye muscles in particular send input to several motor nuclei . Since the progression of ALS tends to start in the upper or lower extremities and progresses proximally, I would guess axon length might be a factor in cell survival. Also, since ALS affects both upper and lower motor neurons, I would guess the eye's redundancy of having several motor nuclei might preserve its motor capacities.