In a way, the uncanny valley has already been crossed-- video game characters in some games are sufficiently humanlike that I hesitate to kill them.
I once watched a video of an Iraqi sniper at work, and it was disturbingly similar to what I see in realistic military video games (I don't play them myself, but I've seen a couple.)
I would like to propose this as a thread for people to write in their predictions for the next year and the next decade, when practical with probabilities attached. I'll probably make some in the comments.