Along the same idea, but much more likely to yield radical differences to the future of human society, I'd like to know what would have happened if some ancient bottleneck epidemic had not happened or had happened differently (killed more or fewer people, or just different individuals). Much or all of the human gene pool after that altered event would be different.
I'd be pretty interested in seeing the results of this set of Malaria-resistance mutations having been more widespread.
And happy new year to everyone.