While I don't think you need to read it, per se, I have found sci fi to be of remarkable use in preparing me for exactly the kind of mind-changing upon which Less Wrong thrives. The Asimov short stories cited above are good examples.

I also continue to cite Asimov's Foundation trilogy (there are more after the trilogy, but he openly said that he wrote the later books purely because his publisher requested them) as the most influential fiction works in pushing me into my current career.