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Christian_Szegedy comments on Savulescu: "Genetically enhance humanity or face extinction" - Less Wrong
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I am very skeptical about any human gene-engineering proposals (for anything other than targeted medical treatment purposes.)
Even if we disregard superhuman artificial intelligences, there are a lot of more direct and therefore much quicker prospective technologies in sight: electronic/chemical brain-enhancing/control, digital supervision technologies, memetic engineering, etc.
IMO, the prohibitively long turnaround time of large scale genetic engineering and its inherently inexact (indirect) nature makes it inferior to almost any thinkable alternatives.
We have had successful trials of gene therapy in the last year to let apes see additional colors. We will have the possibility to sequence the gene of all of humanity sometimes in the next decade. We will have the tech to choose to do massive testing and correlate the test scores with genes and develop gene therapy to switch those genes off in the next decade.
If we don't have ethical problems with doing so we could probably start pilot trials at the end of this decade for genetical engineering with gene therapy.