gregconen comments on Savulescu: "Genetically enhance humanity or face extinction" - Less Wrong
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From the perspective of the universe at large, humans are at best an interesting anomaly. Humans, plus all domesticated animals, crops, etc, compose less than 2% of the earth's biomass. The entire biomass is a few parts per billion of the earth (maybe it's important as a surface feature, but life is still outmassed by about a million times by the oceans and a thousand times by the atmosphere). The earth itself is a few parts per million of the solar system, which is one of several billion like it in the galaxy.
All of the mass in this galaxy, and all the other galaxy, quasars, and other visible collections of matter, are outmassed five to ten times by hydrogen atoms in intergalactic space.
And all that, all baryonic matter, composes a few percent of the mass-energy of the universe.