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DonGeddis comments on Open Thread: February 2010 - Less Wrong
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Fun sneaky confidence exercise (reasons why exercise is fun and sneaky to be revealed later):
Please reply to this comment with your probability level that the "highest" human mental functions, such as reasoning and creative thought, operate solely on a substrate of neurons in the physical brain.
With a straightforward interpretation of your question, I'd answer "95%".
But since you made special mention of being "sneaky", I'll assume you've attempted to trick me into misunderstanding the question, and so I'll lower my probability estimate to 75%, with the missing twenty points accounting for you tricking me by your phrasing of the question.