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Torben comments on Open Thread: February 2010 - Less Wrong
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Fun sneaky confidence exercise (reasons why exercise is fun and sneaky to be revealed later):
Please reply to this comment with your probability level that the "highest" human mental functions, such as reasoning and creative thought, operate solely on a substrate of neurons in the physical brain.
1%. I find the question ambiguous. Glial cells very likely have a major effect (I assume it's not part of the exercise to look it up).
This is discounting blood vessels and other necessary logistics.