Splat: Thanks for this; it's enlightening and useful.
The part I'm not convinced of this:
to simulate any biological creature, you need N plus a bunch of biological information
A squirrel is a finite structure; it can be specified by a sequence of A's, C's, G's and T's, plus some rules for protein synthesis and a finite number of other facts about chemistry. (Or if you think that leaves something out, it can be described by the interactions among a large but finite collection of atoms.) So I don't see where we need all of N to simulate a squirrel.
Well, if you need to simulate a squirrel for just a little while, and not for unbounded lengths of time, a substructure of N (without closure under the operations) or a structure with a considerable amount of sharing with N (like 64-bit integers on a computer) could suffice for your simulation.
The problem you encounter here is that these substructures and near-substructures, once they reach a certain size, actually require more information to specify than N itself. (How large this size is depends on which abstract computer you used to define your instance...
A monthly thread for posting rationality-related quotes you've seen recently (or had stored in your quotesfile for ages).
ETA: It would seem that rationality quotes are no longer desired. After several days this thread stands voted into the negatives. Wolud whoever chose to to downvote this below 0 would care to express their disapproval of the regular quotes tradition more explicitly? Or perhaps they may like to browse around for some alternative posts that they could downvote instead of this one? Or, since we're in the business of quotation, they could "come on if they think they're hard enough!"