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gregconen comments on The Craigslist Revolution: a real-world application of torture vs. dust specks OR How I learned to stop worrying and create one billion dollars out of nothing - Less Wrong
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Be that as it may, there exist above-average charities which have a net positive impact. If we select among those charities (or choose a grantmaker likely to select above-average charities), ,we can have a net positive impact.