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CarlShulman comments on The Craigslist Revolution: a real-world application of torture vs. dust specks OR How I learned to stop worrying and create one billion dollars out of nothing - Less Wrong
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Head to Givewell.net, the Poverty Action Lab, and www.dcp2.org. If you want to expect to save one life with high confidence today (and don't care about future generations/x-risk, research, advocacy, and other approaches with apparently higher expected value) the figure is on the close order of $1,000.