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Although the evidence is far from conclusive, regular caffeine consumption may have neuroprotective effects, perhaps more likely among women and older people.
Ritchie K, Carrière I, de Mendonca A, Portet F, Dartigues JF, Rouaud O, Barberger-Gateau P, Ancelin ML. The neuroprotective effects of caffeine: a prospective population study (the Three City Study). Neurology. 2007 Aug 7;69(6):536-45.
Rosso A, Mossey J, Lippa CF. Caffeine: neuroprotective functions in cognition and Alzheimer's disease. Am J Alzheimers Dis Other Demen. 2008 Oct-Nov;23(5):417-22.
Corley J, Jia X, Kyle JA, Gow AJ, Brett CE, Starr JM, McNeill G, Deary IJ. Caffeine consumption and cognitive function at age 70: the Lothian Birth Cohort 1936 study. Psychosom Med. 2010 Feb;72(2):206-14. Epub 2009 Dec 7.