wedrifid comments on Coffee: When it helps, when it hurts - Less Wrong
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I asked my wife, an ICU nurse, about this combination of drugs as a concentration enhancer/weight loss tool. According to her, use of ephedrine in anything but a medical emergency is a really bad idea. Wrong dosing/accelerated uptake due to other factors could mean a heart attack really really easily. Probably you already know this, but I can't assume.
She also told me that, if you are going to choose a strong stimulant, there are a lot better choices than ephedrine (sorry, forgot specifics).
I presume knb has done enough research to know how not to give himself ten times the safe dose.