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ciphergoth comments on Undiscriminating Skepticism - Less Wrong
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Why would you take such a pill? So that you can have more fun, or for some other reason?
So I wouldn't miss out on half the fun.
How do you distinguish the sort of fun it's worth changing your values to enjoy from the sort of fun (like wireheading) it's worth not having access to?
Of course, it's nothing like half the fun you're missing. Adding a gender would increase your fun by less than 100% since it's not that different in many ways. Adding all the sexual variation in the world would be a humongous amount of fun, but you'd start to hit diminishing returns after a while.