mattnewport comments on Let There Be Light - Less Wrong
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I find the factors for the big 5 a little odd in that they seem to be arranged in clear good/bad pairs, unlike Myers-Briggs which seems to be more arranged as 'not better, just different'. Maybe I'm suffering from some kind of bias but it seems like one would want to score highly on openness, conscientiousness, extroversion and agreeableness and low on neuroticism. They look more like D&D ability scores than alignments.
Attempts have been made to reduce the Big Five into a "Big One", or "General Factor of Personality"(GFP), this correlates the way you describe it. The neurotism is sometimes called Stability, and this together with the other four correlate with one another. Here's a paper by Rushton et al:
(I have low GFP: I'm rather miserable...)