JamesAndrix comments on Open Thread: April 2010 - Less Wrong
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At the risk of repeating the same mistake as my previous comment, I'll do armchair genetics this time:
Perhaps genes controlling the size of various mammalian organs and body regions tend to grow or shrink uniformly, and only become disproportionate when there is a stronger evolutionary pressure. When there is a mutation leading to more growth, all the organs tend to grow more.