An Open Thread: a place for things foolishly April, and other assorted discussions.
This thread is for the discussion of Less Wrong topics that have not appeared in recent posts. If a discussion gets unwieldy, celebrate by turning it into a top-level post.
Update: Tom McCabe has created a sub-Reddit to use for assorted discussions instead of relying on open threads. Go there for the sub-Reddit and discussion about it, and go here to vote on the idea.
Theanine may be "one of many compounds found in tea" but, on the recommendation of an acquaintance I tried taking theanine itself as an experiment once (from memory maybe 100mg?). First I read up on it a little and it sounded reasonably safe and possibly beneficial and I drank green tea anyway so it seemed "cautiously acceptable" to see what it was like in isolation. Basically I was wondering if it helped me relax, focus, and/or learn better.
The result was a very dramatic manic high that left me incapable intellectually directed mental focus (as opposed to focus on whatever crazy thing popped into my head and flittered away 30 minutes later) for something like 35 hours. Also, I couldn't sleep during this period.
In retrospect I found it to be somewhat scary and it re-confirmed my general impression of the bulk of "natural" supplements. Specifically, it confirmed my working theory that the lack of study and regulation of supplements leads to a market full of many options that range from worthless placebo to dangerously dramatic, with tragically few things in the happy middle ground of safe efficacy.
Melatonin is one of the few supplements that I don't put in this category, however in that case I use less than "the standard" 3mg dose. When I notice my sleep cycle drifting unacceptably I will spend a night or two taking 1.5mg of melatonin (using a pill cutter to chop 3mg pills in half) to help me fall asleep and then go back to autopilot. The basis for this regime is that my mother worked in a hospital setting and 1.5mg was what various doctors recommended/authorized for patients to help them sleep.
There was a melatonin fad in the late 1990's(?) where older people were taking melatonin as a "youth pill" because endogenous production declines with age. I know of no good studies supporting that use, but around that time was when the results about sleep came out, showing melatonin to be effective even for "jet lag" as a way to reset one's internal clock swiftly and safely.
That reaction sounds rare. Do you think 20 cups of tea would have triggered a similar reaction in you?
There is a huge variation based on dosage for all things you can ingest: food, drug, supplement, and "other". Check out the horrors of eating a whole bottle of nutmeg. http://www.erowid.org/experiences/subs/exp_Nutmeg.shtml