RichardKennaway comments on Open Thread: April 2010 - Less Wrong
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Does brain training work? Not according to an article that has just appeared in Nature. Paper here, video here or here.
Note that they were specifically looking for transfer effects. The specific tasks practised did themselves show improvements.
Brain training, for those not following the link, refers to playing games involving particular mental skills (e.g. memory). The study ran six weeks.
I don't think the experiment looks definite - the control group did not appear as thoroughly distinguished from the test groups as I would have liked - but the MRC Cognition and Brain Sciences Unit (who were partners in the experiment) is well-regarded enough that I would call the null result major evidence.
The fact that they studied adults rather than children may make a difference.