RobinZ comments on Open Thread: April 2010 - Less Wrong
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Brain training, for those not following the link, refers to playing games involving particular mental skills (e.g. memory). The study ran six weeks.
I don't think the experiment looks definite - the control group did not appear as thoroughly distinguished from the test groups as I would have liked - but the MRC Cognition and Brain Sciences Unit (who were partners in the experiment) is well-regarded enough that I would call the null result major evidence.