Another thing that's not discussed that much is whether the various behavior adjustment systems that initially work keep working over time. I'd guess that the brain reacts differently to a system it's become quite familiar with than a new one.

On one hand, a system might just turn from explicitly followed behavior into an unconscious habit that keeps working against akrasia. This would be a good thing. On the other hand, there could be tricks that work while the brain isn't very familiar with them, but once they become known, the brain just figures out a way around them and they end up not being much use.