gwern comments on 23andme genome analysis - $99 today only - Less Wrong
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What do you think you might learn? I haven't seen very many practical results (as opposed to idle curiosity), except for a few things like lactose intolerance.
EDIT: I've since seen a number of interesting examples - warfarin sensitivity and how well modafinil works come to mind. The latter, since modafinil is pretty expensive, might justify testing at $100 or $200 all on its own.