Nisan comments on Open Thread: May 2010 - Less Wrong
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the most extreme example is depressed people having an increased risk of suicide if an antidepressant lifts their akrasia before it improves their mood.
Interesting. Are you sure that is going on when antidepressants have paradoxical effects?
Not absolutely certain. It's an impression I've picked up from mass media accounts, and it seems reasonable to me.
It would be good to have both more science and more personal accounts.
Thanks for asking.
My mom is a psychiatrist, and she's given an explanation basically equivalent to that one - that people with very severe depression don't have the "energy" to do anything at all, including taking action to kill themselves, and that when they start taking medication, they get their energy back and are able to act on their plans.