You make a fair point that PUA probably doesn't explain all of human interaction - it explains just the bare minimum needed to get that 1 in 50 hit rate, so the majority of girls could be PUA-invulnerable and we wouldn't know it. But you also claim that a hit rate of 1 in 50 is bad and shouldn't be considered a "win", and I take objection to this. Do you also think that a good mathematician should be able to solve any problem in the world or give up their title? Or do you have an alternative theory that can beat PUA at PUA's game? (Then you should head over to their forums and if you're right, they will adopt your theory en masse.) If not, why should we suppress the best theory we've got at the moment?
You say a hit rate of 1 in 50 is bad and shouldn't be considered a "win". Do you also think that a good mathematician should be able to solve any problem in the world or give up their title?
If I apply the same methods for the same amount of time to many problems, and I solve only 1 in 50 of them, then I should seriously consider the possibility that there was something special about that 1 in 50 that made them especially accessible to my methods. I should not conclude that the 1 in 50 were typical of all the problems that I considered.
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Followup to: Do you have High-Functioning Asperger's Syndrome?
LW reader Madbadger uses the metaphor of a GPU and a CPU in a desktop system to think about people with Asperger's Syndrome: general intelligence is like a CPU, being universal but only mediocre at any particular task, whereas the "social coprocessor" brainware in a Neurotypical brain is like a GPU: highly specialized but great at what it does. Neurotypical people are like computers with measly Pentium IV processors, but expensive Radeon HD 4890 GPUs. A High-functioning AS person is an Intel Core i7 Extreme Edition - with on-board graphics!
This analogy also covers the spectrum view of social/empathic abilities, you can think about having a weaker social coprocessor than average if you have some of the tendencies of AS but not others. You can even think of your score on the AQ Test as being like the Tom's Hardware Rating of your Coprocessor. (Lower numbers are better!).
If you lack that powerful social coprocessor, what can you do? Well, you'll have to run your social interactions "in software", i.e. explicitly reason through the complex human social game that most people play without ever really understanding. There are several tricks that a High-functioning AS person can use in this situation: