If your goal is to pick up women, then yes, absolutely 1 in 50 is a "win". But if your goal is to refine the art of human rationality, I just don't see how it's relevant.
The thing is, with any model (PUA or otherwise), there are many reasons you could lose out on the 49 in 50 (to go with your terminology for now):
They aren't into your body type, facial structure, height, race, or some other superficial characteristic
They have preferences that are explained by your model, but you messed up or otherwise failed to fulfill them (Similarly: they have preferences that are explained by your model, but you didn't go far enough in following the model.) This is exacerbated by the tendency of people to go for partners at the edge
Followup to: Do you have High-Functioning Asperger's Syndrome?
LW reader Madbadger uses the metaphor of a GPU and a CPU in a desktop system to think about people with Asperger's Syndrome: general intelligence is like a CPU, being universal but only mediocre at any particular task, whereas the "social coprocessor" brainware in a Neurotypical brain is like a GPU: highly specialized but great at what it does. Neurotypical people are like computers with measly Pentium IV processors, but expensive Radeon HD 4890 GPUs. A High-functioning AS person is an Intel Core i7 Extreme Edition - with on-board graphics!
This analogy also covers the spectrum view of social/empathic abilities, you can think about having a weaker social coprocessor than average if you have some of the tendencies of AS but not others. You can even think of your score on the AQ Test as being like the Tom's Hardware Rating of your Coprocessor. (Lower numbers are better!).
If you lack that powerful social coprocessor, what can you do? Well, you'll have to run your social interactions "in software", i.e. explicitly reason through the complex human social game that most people play without ever really understanding. There are several tricks that a High-functioning AS person can use in this situation: