"If you're kind of good at (or interested in) analytical things, and kind of bad at (or uninterested in) social things, you'll specialize your own brain in that direction. It may even be in your best interest to specialize to some extent, to play to your strengths."
I agree with this. I would also like to add, especially with higher-functioning autistics , that they are quite aware of the practicality of social skills and status, and if wrongplanet users are any indicator, many if not most want to be genuinely socially adept. Regarding the NT vs. AS model, here are a couple possible reasons as to why NTs have better social skills: 1) It is unconscious and hard-wired, or 2) due to being more vigilant for social cues and body-language, learn the rules of the game earlier in life and reap the benefits as a result. I prefer the latter explanation, because it means one can be socially competent once these rules are taught.
Followup to: Do you have High-Functioning Asperger's Syndrome?
LW reader Madbadger uses the metaphor of a GPU and a CPU in a desktop system to think about people with Asperger's Syndrome: general intelligence is like a CPU, being universal but only mediocre at any particular task, whereas the "social coprocessor" brainware in a Neurotypical brain is like a GPU: highly specialized but great at what it does. Neurotypical people are like computers with measly Pentium IV processors, but expensive Radeon HD 4890 GPUs. A High-functioning AS person is an Intel Core i7 Extreme Edition - with on-board graphics!
This analogy also covers the spectrum view of social/empathic abilities, you can think about having a weaker social coprocessor than average if you have some of the tendencies of AS but not others. You can even think of your score on the AQ Test as being like the Tom's Hardware Rating of your Coprocessor. (Lower numbers are better!).
If you lack that powerful social coprocessor, what can you do? Well, you'll have to run your social interactions "in software", i.e. explicitly reason through the complex human social game that most people play without ever really understanding. There are several tricks that a High-functioning AS person can use in this situation: