I understand that there is work supporting the idea that cryonics/regeneration/etc. will eventually be successful. However, I don't feel the need to respond to this work very directly, because this work, after all, is very indirect, in the sense that it is only making plausibility arguments. As a cryonics skeptic, I am not attempting to rule out the plausibility or possibility of cryonics. After all, it seems fairly plausible that this stuff will eventually get worked out, as with the usual arguments for technological advancement. As a cryonics skeptic, I am only asserting that there is insufficient evidence that it will work for my personal freezing/revival to justify my substantial investment.

The response to this might be to claim that I am unfairly or erroneously making "demands for particular proof". I think that this point is an intelligent point, but that it is being somewhat abused or overused in this context. In areas like physics or biology, it is completely status-quo to believe nothing except that which has been shown by fairly direct evidence. You might even abstractly characterize the entirety of professional science as an area in which "demands for particular proof" are the centralizing, unifying, distinguishing feature. Seeing as how cryonics is essentially an area of physics and biology, I view it in much the same way. I expect to see more concrete proof of its ability before being willing to believe in it, invest in it, or rely on it for my supposed personal immortality.