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katydee comments on Open Thread, August 2010-- part 2 - Less Wrong
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Two questions:
-How much does it cost?
-How soon do you start becoming desensitized to it, if at all?
I ordered from here at a price of $46 for 500g each of piracetam and choline citrate, plus $10 for gel caps and $20 for a scale (which is independently useful).
I could not find any reported instances of desensitization to piracetam, so I don't think it's an issue.
I'm trying out nootropics, adding them one at a time. Next on my list to try is sulbutiamine; I've seen claims that it prevents mental fatigue, and it too has basically zero side-effect risks. Also on my list to try are lion's mane, aniracetam, l-tyrosine and fish oil. All of these are unregulated in the US.
I also use adrafinil, which greatly improves my focus. However, it's more expensive and it can't be used continuously without extra health risks, so I only use it occasionally rather than as part of my daily regimen. (There's an expensive and prescription-only related drug, modafinil, which can be used continuously.)
Sounds good. Be sure to report back once you test out the others-- nootropics are very interesting to me, and I think generally useful to the community as well.
First, the results of a wikipedia check: "There is very little data on piracetam's effect on healthy people, with most studies focusing on those with seizures, dementia, concussions, or other neurological problems." which seems to decrease the assurance of safety for everyday use. But otherwise, most of the sources appear to agree with your advertising. I too would like to see memory tests for these drugs, but preferably in a large and random sample of people, with a control group given a placebo, and another control group taking the tests with no aid of any kind. As well as a long term test to check for diminishing effectiveness or side effects. With my memory, I would pay a considerable amount to improve it, but first I want to see a wide scale efficiency test.
Working on it. Give me a few years.
Why? Given the low cost and risk of trying it out, the high possible benefits, and the high probability that results will depend on individual genetic or other variations and so will not reach significance in any study, wouldn't the reasonable thing be to try it yourself, even if the wide-scale test had already concluded it had no effect?
Using your logic, I would be forced to try a large proportion of all drugs ever made. My motivation to buy this drug is close to my motivation to buy every other miracle drug out there, I want more third party tests of each one so I can make a more informed decision of where to spend my money, instead of experimenting on hundreds per month. Also, it does not have a DIN number in Canada, so I would need to import it.
A large proportion of drugs ever made have been claimed to improve memory and have a long history of null-results for side-effects and positive results for mental improvement?
Indeed.