In general, any mental health diagnosis is usually conditioned on a significant disruption of the sufferer's life [...] This is usually on the DSM checklist for a diagnosis and while I don't know offhand if ASPD is the same, I'd bet that it is.

It is, yes, but that doesn't necessarily preclude "effective" -- the diagnosis can be based on disruption of any part of the patient's life. It's entirely possible for the behavior associated with a disorder to improve outcomes in one domain (employment, say), while disrupting others (i.e. family life) enough for the label to stick. That's what I was trying to get at with my qualification about occupational success.