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timtyler comments on Problems in evolutionary psychology - Less Wrong
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Probably the single biggest problem for E. P. is that its practitioners typically don't "get" menetics. Pinker is a good example of this.
The issue has been explained in detail in these papers:
Ehrlich, Paul and Feldman, Marcus (2003) Genes and Cultures: What Creates Our Behavioral Phenome? Current Anthropology, Vol 44(1), Feb 2003, 87-107.
Ehrlich, Paul and Feldman, Marcus (2007) Genes, environments & behaviors. Daedalus, Vol. 136, No. 2, Pages 5-12.
The good news is the E. P. and memetics can be bolted together - although the result is then a lot like memetics and not very much like E. P.
The bad news is that without memetics, E. P. is pretty terminally screwed.