Personally I have great hopes for Blue Brain. If it figures out how a single cortex unit works ( which they seem to be on the way to). If they can then figure out how to convert that into a chip and put oodles of those clips in the right environment of inputs and interactions with other parts of the brain (thalamus and basal ganglia especially) and then.....

A lot of work but it has a good chance as long as it avoids the step-by-step algorithm trap.