ChrisHibbert comments on Frugality and working from finite data - Less Wrong
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This is somewhat true of macroeconomics, but manifestly untrue of microeconomics. Economists are constantly doing experiments to learn more about how incentives and settings affect behavior. And the results are being applied in the real world, sometimes in environments where alternative hypotheses can be compared.
And even in macroeconomics, work like that explained in Freakonomics shows how people can compare historical data from polities that chose different policies and learn from the different outcomes. So even if no individual scientist will be allowed to conduct a controlled experiment on the macroeconomy, there are enough competing theories that politicians are constantly following different policies, and providing data that sheds light on the consequences of different choices.