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jimrandomh comments on Intelligence Amplification Open Thread - Less Wrong
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Sulbutiamine. I don't know whether it will return measurable results for typical biochemistries or not, but I'd very much like to know. I'm also unsure what the test procedure for "reduced mental fatigue" would be like. Maybe give subjects control over their breaks and stopping point for a task, and measure their persistence?
Anecdote: I've tried out sulbutiamine (250-400 mg mixed with 2g piracetam) from smartpowders and didn't notice a difference -- certianly not the momentous results you obtained. However, I'm not diabetic (just fat, quick to sweat, and tired after eating).