A place to discuss potentially promising methods of intelligence amplification in the broad sense of general methods, tools, diets, regimens, or substances that boost cognition (memory, creativity, focus, etc.): anything from SuperMemo to Piracetam to regular exercise to eating lots of animal fat to binaural beats, whether it works or not. Where's the highest expected value? What's easiest to make part of your daily routine? Hopefully discussion here will lead to concise top level posts describing what works for a more self-improvement-savvy Less Wrong.
Lists of potential interventions are great, but even better would be a thorough analysis of a single intervention: costs, benefits, ease, et cetera. This way the comment threads will be more structured and organized. Less Wrong is pretty confused about IA, so even if you're not an expert, a quick analysis or link to a metastudy about e.g. exercise could be very helpful.
Added: Adam Atlas is now hosting an IA wiki: BetterBrains! Bookmark it, add to it, make it awesome.
For an interface to a computer, I completely agree; mice are for art and play, keyboards are for getting other work done.
However, while I have excellent touchtyping speed and a small portable netbook, I still take class notes, and often brainstorm, on paper. Why? It's the easiest possible way to work in two dimensions. I can make outlines, add margin notes, connect related ideas with arrows, and draw diagrams, without being confined to a grid or having to switch modes between location selection and input. I don't know of and have difficulty imagining the computer program that would let me do this anywhere near as fluidly, although if someone knows one I'd love to hear about it.
Another benefit is that you will remember your notes better if you write them on paper. The kinaesthetic involvement aids memory formation. I don't do it myself. But then, I don't usually take notes either.