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Relsqui comments on Intelligence Amplification Open Thread - Less Wrong
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My experience is that when used in combination with sufficient sleep, i.e., much more sleep than most Americans get, small doses of caffeine (e.g. 1 espresso/day) can be a permanently useful stimulant. The 'cost' of the alertness gets taken out of your bone density and immune system rather than via chemical habituation.
I'll still take a pass. :)