A place to discuss potentially promising methods of intelligence amplification in the broad sense of general methods, tools, diets, regimens, or substances that boost cognition (memory, creativity, focus, etc.): anything from SuperMemo to Piracetam to regular exercise to eating lots of animal fat to binaural beats, whether it works or not. Where's the highest expected value? What's easiest to make part of your daily routine? Hopefully discussion here will lead to concise top level posts describing what works for a more self-improvement-savvy Less Wrong.
Lists of potential interventions are great, but even better would be a thorough analysis of a single intervention: costs, benefits, ease, et cetera. This way the comment threads will be more structured and organized. Less Wrong is pretty confused about IA, so even if you're not an expert, a quick analysis or link to a metastudy about e.g. exercise could be very helpful.
Added: Adam Atlas is now hosting an IA wiki: BetterBrains! Bookmark it, add to it, make it awesome.
Focus is sometimes tested by giving people a task and introducing distracting influences in a controlled manner. I recall nicotine being tested on children in this way (it works about as well as Adderall if memory serves me.) But there isn't too much incentive for people to formally research this kind of thing for most nootropics so a lot of the time we just have ad hoc anecdotal reports to go by.
Modafinil is better for boosting mood than caffeine or adderall, especially in as much as it tends to provoke less agitation. The effect on focus is not quite as pronounced as with the amphetamine. This is sometimes considered a good thing when the overfocus is detrimental (eg. when socialising or exposed to TvTropes.)
Selegeline also improves both focus and mood - in a more subtle way over periods of weeks (irreversible MAOB inhibition doesn't 'rebound' after a few hours).
For mood specifically try Phenylethylamine while you are taking selegeline (carefully!) or use phenibut.