AndrewHickey comments on Intelligence Amplification Open Thread - Less Wrong

46 Post author: Will_Newsome 15 September 2010 08:39AM

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Comment author: [deleted] 16 September 2010 09:50:21PM 5 points [-]

I'd be VERY careful with 5-HTP . Very careful indeed. I used it for a couple of years and it had some beneficial effects (increased sleep, decreased migraine, decreased depression, general cognitive improvement). But anything that affects your serotonergetic system can have nasty unpredictable effects. In my case, I upped my caffeine intake a lot, without realising that caffeine can have a synergetic effect with 5-HTP, and gave myself mild <a href="http://en.wikipedia.org/wiki/Serotonin_syndrome">serotonin syndrome</a>. NOT pleasant. In particular, if you take any kind of SSRI, don't touch 5-HTP with a bargepole...