Emile comments on Rationality Power Tools - Less Wrong
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It is less uncertain, but be careful to distinguish between uploads and emulation. Emulation just takes being able to scan at a sufficient level to get something brain-like; uploading requires getting sufficient resolution to get actual personalities and the like. It's intuitively probable that you can get dangerous neuromorphic AI via emulation before you can get a fully emulated previously in-the-flesh human specific simulation that would count as an 'upload'. But I don't have a strong technical argument for that proposition. Perhaps the Whole Brain Emulation Roadmap (PDF) would have more to say.
In my mind the distance between the resolution necessary to make something brain-like and functional, and the resolution necessary to make a perfect copy of the target brain is not very large - at least, not large enough to have a big difference in expected time of arrival.
By analogy to a computer: once you can scan and copy a computer well enough for the copy to function, you're not very far from being able to make a copy that's functionally equivalent.
Bearing in mind that we created computers in such a way that copying is easy. And we created them digital and use checksums.