I have seen some reports online about grad students using beta blockers to prevent outward signs of anxiety during their oral exams, so a beta blocker might be useful for (4).
Beta blockers only really work for physical anxiety (the canonical example being classical musicians taking them to prevent trembling hands before concerts). Benzodiazepines work for both physical anxiety and mental anxiety, which is better for pickup. The lowered inhibitions of xanax/klonopin/valium is comparable to alcohol, but with fewer immediate side effects (less loss of coordination, etc.).
We operate like this: the "overseer process" tells the brain, using blunt instruments like chemicals, that we need to find something to eat, somewhere to sleep or someone to mate with. Then the brain follows orders. Unfortunately the orders we receive from the "overseer" are often wrong, even though they were right in the ancestral environment. It seems the easiest way to improve humans isn't to augment their brains - it's to send them better orders, e.g. using drugs. Here's a list of fantasy brain-affecting drugs that I would find useful, even though they don't seem to do anything complicated except affecting "overseer" chemistry:
1) A drug against unrequited love, aka "infatuation" or 'limerence".
2) A drug that makes you become restless and want to exercise.
3) A drug that puts you in the state of random creativity that you normally experience just before falling asleep.
4) A drug that puts you in the optimal PUA "state".
5) A drug that boosts your feeling of curiosity. Must be great for doing math or science.
Anything else?