Not really. An AI that didn't have a specific desire to be friendly to mankind would want to kill us to cut down on unnecessary entropy increases.
An AI that that had a botched or badly preserved Friendliness, or that was unfriendly but had been initialized with supergoals involving humans, may well have specific, unpleasant, non-extermination plans for humans.
http://www.youtube.com/watch?v=ghIj1mYTef4