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Kevin comments on Best career models for doing research? - Less Wrong
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If you think there is a significant probability that an intelligence explosion is possible or likely, then that question is sensitive to how well things go on Earth in the next 100 years.
However likely they are, I expect intelligence explosions to be evenly distributed through space and time. If 100 years from now Earth loses by a hair, there are still plenty of folks around the universe who will win or have won by a hair. They'll make whatever use of the 80 billion galaxies that they can--will they be wasting them?
If Earth wins by a hair, or by a lot, we'll be competing with those folks. This also significantly reduces the opportunity cost Roko was referring to.